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KMID : 0043319850080040277
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Archives of Pharmacal Research
1985 Volume.8 No. 4 p.277 ~ p.282
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Effects of Antitumor Polysaccharides from Albizza julibrissin on Immune Function
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Moon CK
Lee BG/Lee SH/Kang TL
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Abstract
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Polysaccharide fractions were prepared from Albizza julibrissin by different extraction schedules. The fractions obtained were designated as PS-I and PS-II, respectively. Further purification of PS-I by Sephadex G-200 column chromatography gave two subtractions, Alju A and Alju B. Each fraction :Showed marked antitumor activity against sarcoma 180 solid form but not ascite form. PS-I and PS-II increased delayed hypersensitivity in normal and tumor bearing mice. PS-I treatment led to moderate restoration of the suppressed antibody production in tumor bearing mice.
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